Anti-RAMP1 Polyclonal Antibody
品牌：solarbio | 货号：K008222P
| 英文名称 | Anti-RAMP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | Receptor activity-modifying protein 1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:10-50. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 17kDa |
| Gene ID | 10267 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RAMP1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RAMP1 |
| Subcellular Locations | Membrane Cytoplasm |
| Swiss Prot | O60894 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface. |