Anti-SIRT1 Polyclonal Antibody
品牌：solarbio | 货号：K000319P
| 英文名称 | Anti-SIRT1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SIR2;SIR2L1;SIR2alpha |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 蛋白分子量 | 82kDa |
| Gene ID | 23411 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human SIRT1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human SIRT1 |
| Subcellular Locations | Cytoplasm Mitochondrion Nucleus Nucleus PML body |
| Swiss Prot | Q96EB6 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |