Anti-FZD7 Polyclonal Antibody
品牌：solarbio | 货号：K003765P
| 英文名称 | Anti-FZD7 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FzE3 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 64kDa |
| Gene ID | 8324 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human FZD7 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human FZD7 |
| Subcellular Locations | Cell membrane Membrane Multi-pass membrane protein |
| Swiss Prot | O75084 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Members of the ‘frizzled’ gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. |