Anti-GEMIN2 Polyclonal Antibody
品牌：solarbio | 货号：K003584P
| 英文名称 | Anti-GEMIN2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | SIP1;SIP1-delta |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-1000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 32kDa |
| Gene ID | 8487 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human GEMIN2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human GEMIN2 |
| Subcellular Locations | Cytoplasm Nucleus gem |
| Swiss Prot | O14893 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. |