Anti-ZAP-70 Monoclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ZAP-70 Monoclonal Antibody

品牌:solarbio | 货号:K007477P

英文名称 Anti-ZAP-70 Monoclonal Antibody
宿主 Rabbit
别名 SRK;STD;TZK;STCD;IMD48;ADMIO2;ZAP-70
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-300.
交叉反应 Human Mouse
蛋白分子量 70kDa
Gene ID 7535
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ZAP70
性状 液体
Public Immunogen Range Recombinant protein of human ZAP70
Subcellular Locations Cytoplasm
Swiss Prot P43403
克隆类型 Polyclonal Antibody
背景资料 This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.