Anti-SKAP2 Polyclonal Antibody
品牌：solarbio | 货号：K004525P
| 英文名称 | Anti-SKAP2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PRAP;RA70;SAPS;SCAP2;SKAP-HOM;SKAP55R |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. IF 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 41kDa |
| Gene ID | 8935 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human SKAP2 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human SKAP2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | O75563 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. |