Anti-CTTN Polyclonal Antibody
品牌：solarbio | 货号：K107018P
| 英文名称 | Anti-CTTN Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EMS1,cortactin |
| 应用 | WB IHC |
| 稀释比例 | WB 1:8000-12000. IHC 1:50-200. |
| 交叉反应 | Human |
| 蛋白分子量 | 62/71/57kDa |
| Gene ID | 2017 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human CTTN |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human CTTN |
| Subcellular Locations | Cytoplasm? |
| Swiss Prot | Q14247 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. |