Anti-CTTN Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CTTN Polyclonal Antibody

品牌:solarbio | 货号:K107018P

英文名称 Anti-CTTN Polyclonal Antibody
宿主 Rabbit
别名 EMS1,cortactin
应用 WB IHC
稀释比例 WB 1:8000-12000. IHC 1:50-200.
交叉反应 Human
蛋白分子量 62/71/57kDa
Gene ID 2017
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CTTN
性状 液体
Public Immunogen Range A synthetic peptide of human CTTN
Subcellular Locations Cytoplasm?
Swiss Prot Q14247
克隆类型 Polyclonal Antibody
背景资料 This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.