Anti-MCPIP1 Polyclonal Antibody
品牌：solarbio | 货号：K106615P
| 英文名称 | Anti-MCPIP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | dJ423B22.1;MCPIP;MCPIP1;dJ423B22.1;MCPIP;MCPIP-1;MCPIP1;Reg1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:20-50. |
| 交叉反应 | Human |
| 蛋白分子量 | 67kDa |
| Gene ID | 80149 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human MCPIP1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human MCPIP1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q5D1E8 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Endoribonuclease involved in various biological functions such as cellular inflammatory response and immune homeostasis, glial differentiation of neuroprogenitor cells, cell death of cardiomyocytes, adipogenesis and angiogenesis. Functions as an endoribonuclease involved in mRNA decay. Modulates the inflammatory response by promoting the degradation of a set of translationally active cytokine-induced inflammation-related mRNAs, such as IL6 and IL12B, during the early phase of inflammation. Prevents aberrant T-cell-mediated immune reaction by degradation of multiple mRNAs controlling T-cell activation, such as those encoding cytokines (IL6 and IL2), cell surface receptors (ICOS, TNFRSF4 and TNFR2) and transcription factor (REL) (By similarity). |