Anti-VEGFR1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-VEGFR1 Polyclonal Antibody

品牌:solarbio | 货号:K106558P

英文名称 Anti-VEGFR1 Polyclonal Antibody
宿主 Rabbit
别名 Emrk2;Flt;Flt1;EC 2.7.10.1;Fms like tyrosine kinase 1
应用 WB
稀释比例 WB 1:3000.
交叉反应 Human Mouse Rat
蛋白分子量 120kDa
Gene ID 14254
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human VEGFR1
性状 液体
Public Immunogen Range A synthetic peptide of human VEGFR1
Subcellular Locations Cell membrane
Swiss Prot P35969
克隆类型 Polyclonal Antibody
背景资料 VEGF Receptor 1 (also known as FLT) belongs to the src gene family and shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The protein acts as a receptor for VEGF, VEGFB and PGF. An alternatively spliced form of the gene produces a soluble protein (sFlt1) which binds vascular endothelial growth factor (VEGF) with high affinity. sFlt1 has a higher affinity for VEGF indicating that it may function as an inhibitor in the VEGF response. VEGF Receptor 1 is specifically expressed in most vascular endothelial cells and peripheral blood monocytes.