Anti-COX7A2L Polyclonal Antibody
品牌:solarbio | 货号:K008131P
英文名称 |
Anti-COX7A2L Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EB1;SIG81;COX7AR;COX7RP |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:30-150. |
交叉反应 |
Human Mouse |
蛋白分子量 |
13kDa |
Gene ID |
9167 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Full length Recombinant protein |
性状 |
液体 |
Public Immunogen Range |
Full length Recombinant protein |
Subcellular Locations |
Mitochondrion inner Membrane |
Swiss Prot |
O14548 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. |