Anti-COX11 Polyclonal Antibody
品牌:solarbio | 货号:K008132P
英文名称 |
Anti-COX11 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
COX11P |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:25-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
31kDa |
Gene ID |
1353 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human COX11 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human COX11 |
Subcellular Locations |
Cytoplasm Membrane |
Swiss Prot |
Q9Y6N1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.? |