Anti-STAU1 Polyclonal Antibody
品牌：solarbio | 货号：K003755P
| 英文名称 | Anti-STAU1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PPP1R150;STAU |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 63kDa |
| Gene ID | 6780 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human STAU1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human STAU1 |
| Subcellular Locations | Cytoplasm Rough endoplasmic reticulum |
| Swiss Prot | O95793 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5’UTR. |