Anti-UBP1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-UBP1 Polyclonal Antibody

品牌:solarbio | 货号:K007758P

英文名称 Anti-UBP1 Polyclonal Antibody
宿主 Rabbit
别名 LBP1A;LBP1B;LBP-1B;LBP-1a
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 60kDa
Gene ID 7342
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human UBP1
性状 液体
Public Immunogen Range A synthetic peptide of human UBP1
Subcellular Locations Nucleus
Swiss Prot Q9NZI7
克隆类型 Polyclonal Antibody
背景资料 LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family). LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.?