Anti-UBP1 Polyclonal Antibody
品牌:solarbio | 货号:K007758P
英文名称 |
Anti-UBP1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
LBP1A;LBP1B;LBP-1B;LBP-1a |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
60kDa |
Gene ID |
7342 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human UBP1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human UBP1 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q9NZI7 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family). LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.? |