Anti-UBP1 Polyclonal Antibody
品牌:solarbio | 货号:K007758P
| 英文名称 | Anti-UBP1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | LBP1A;LBP1B;LBP-1B;LBP-1a |
| 应用 | WB IHC |
| 稀释比例 | WB 1:200-1000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 60kDa |
| Gene ID | 7342 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human UBP1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human UBP1 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q9NZI7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | LBP1 (Upstream-binding protein 1), also designated UBP1, LBP1A or LBP1B, is a 540 amino acid protein that belongs to the grh/CP2 family (grainyhead transcription factor family). LBP1 is a transcriptional activator that regulates the placental expression of CYP11A1 and activates the Hemoglobin globin promoter in erythroid cells. LBP1 is responsible for repressing transcription of HIV-1 by binding to and preventing TFIID from interacting with its promoter region. Null expression of LBP1 causes uterine growth retardation in mice embryos suggesting a critical role in extraembryonic angiogenesis.? |