Anti-DEFA1 Polyclonal Antibody
品牌:solarbio | 货号:K007418P
英文名称 |
Anti-DEFA1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HP1;MRS;DEF1;HP-1;DEFA2;HNP-1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-1000. IHC 1:25-50. |
交叉反应 |
Human |
蛋白分子量 |
10kDa |
Gene ID |
1667 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human DEFA1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human DEFA1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
P59665 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. |