Anti-PTRH2 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PTRH2 Polyclonal Antibody

品牌:solarbio | 货号:K007153P

英文名称 Anti-PTRH2 Polyclonal Antibody
宿主 Rabbit
别名 BIT1;PTH2;CFAP37;CGI-147
应用 WB IHC
稀释比例 WB 1:1000-5000. IHC 1:10-50.
交叉反应 Human Mouse
蛋白分子量 19kDa
Gene ID 51651
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PTRH2
性状 液体
Public Immunogen Range Recombinant protein of human PTRH2
Subcellular Locations Cytoplasm
Swiss Prot Q9Y3E5
克隆类型 Polyclonal Antibody
背景资料 PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.?