Anti-PTRH2 Polyclonal Antibody
品牌:solarbio | 货号:K007153P
英文名称 |
Anti-PTRH2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
BIT1;PTH2;CFAP37;CGI-147 |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:10-50. |
交叉反应 |
Human Mouse |
蛋白分子量 |
19kDa |
Gene ID |
51651 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PTRH2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PTRH2 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
Q9Y3E5 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis.? |