Anti-PTPRE Polyclonal Antibody
品牌：solarbio | 货号：K006827P
| 英文名称 | Anti-PTPRE Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PTPE;HPTPE;R-PTP-EPSILON |
| 应用 | IHC |
| 稀释比例 | IHC 1:15-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 81kDa |
| Gene ID | 5791 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PTPRE |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PTPRE |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P23469 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. |