Anti-MUTYH Polyclonal Antibody
品牌:solarbio | 货号:K006797P
英文名称 |
Anti-MUTYH Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
MYH |
应用 |
WB IHC |
稀释比例 |
WB 1:1000-5000. IHC 1:50-200. |
交叉反应 |
Human |
蛋白分子量 |
60kDa |
Gene ID |
4595 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human MUTYH |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human MUTYH |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q9UIF7 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. |