Anti-STAT6 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-STAT6 Polyclonal Antibody

品牌:solarbio | 货号:K006647P

英文名称 Anti-STAT6 Polyclonal Antibody
宿主 Rabbit
别名 STAT6B;STAT6C;D12S1644;IL-4-STAT
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 94kDa
Gene ID 6778
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human STAT6
性状 液体
Public Immunogen Range Recombinant protein of human STAT6
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P42226
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.