Anti-NCR1 Polyclonal Antibody
品牌：solarbio | 货号：K006353P
| 英文名称 | Anti-NCR1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CD335;LY94;NK-p46;NKP46 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 34kDa |
| Gene ID | 9437 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human NCR1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human NCR1 |
| Subcellular Locations | Cell membrane Single-pass type I membrane protein |
| Swiss Prot | O76036 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |