Anti-ANAPC10 Polyclonal Antibody
品牌:solarbio | 货号:K005762P
| 英文名称 | Anti-ANAPC10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | APC10;DOC1 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 21kDa |
| Gene ID | 10393 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ANAPC10 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ANAPC10 |
| Subcellular Locations | Cytosol Nucleus |
| Swiss Prot | Q9UM13 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]). |