Anti-ANAPC10 Polyclonal Antibody
品牌:solarbio | 货号:K005762P
英文名称 |
Anti-ANAPC10 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
APC10;DOC1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
21kDa |
Gene ID |
10393 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ANAPC10 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ANAPC10 |
Subcellular Locations |
Cytosol Nucleus |
Swiss Prot |
Q9UM13 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]). |