Anti-ARHGEF11 Polyclonal Antibody
品牌：solarbio | 货号：K005581P
| 英文名称 | Anti-ARHGEF11 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | GTRAP48;PDZ-RHOGEF |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 168kDa |
| Gene ID | 9826 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human ARHGEF11 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human ARHGEF11 |
| Subcellular Locations | Cytoplasm Membrane |
| Swiss Prot | O15085 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. |