Anti-POU5F1 Polyclonal Antibody
品牌：solarbio | 货号：K005554P
| 英文名称 | Anti-POU5F1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | OCT3;OCT4;OTF-3;OTF3;OTF4;Oct-3;Oct-4 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 39kDa |
| Gene ID | 5460 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human POU5F1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human POU5F1 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q01860 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing’s sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. |