Anti-ATP6V1B2 Polyclonal Antibody
品牌:solarbio | 货号:K003693P
英文名称 |
Anti-ATP6V1B2 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ATP6B1B2;ATP6B2;DOOD;HO57;VATB;VPP3;Vma2;ZLS2 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
57kDa |
Gene ID |
526 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ATP6V1B2 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ATP6V1B2 |
Subcellular Locations |
Endomembrane system Melanosome Peripheral membrane protein |
Swiss Prot |
P21281 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts. |