Anti-ATP2A1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ATP2A1 Polyclonal Antibody

品牌:solarbio | 货号:K007768P

英文名称 Anti-ATP2A1 Polyclonal Antibody
宿主 Rabbit
别名 ATP2A;SERCA1
应用 WB IHC
稀释比例 WB 1:200-1000. IHC 1:50-200.
交叉反应 Human Mouse
蛋白分子量 110kDa
Gene ID 487
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human ATP2A1
性状 液体
Public Immunogen Range A synthetic peptide of human ATP2A1
Subcellular Locations Cytoplasm
Swiss Prot O14983
克隆类型 Polyclonal Antibody
背景资料 This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.?