Anti-ATP2A1 Polyclonal Antibody
品牌:solarbio | 货号:K007768P
英文名称 |
Anti-ATP2A1 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ATP2A;SERCA1 |
应用 |
WB IHC |
稀释比例 |
WB 1:200-1000. IHC 1:50-200. |
交叉反应 |
Human Mouse |
蛋白分子量 |
110kDa |
Gene ID |
487 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human ATP2A1 |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human ATP2A1 |
Subcellular Locations |
Cytoplasm |
Swiss Prot |
O14983 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.? |