Anti-RAD18 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-RAD18 Polyclonal Antibody

品牌:solarbio | 货号:K003956P

英文名称 Anti-RAD18 Polyclonal Antibody
宿主 Rabbit
别名 RNF73
应用 WB
稀释比例 WB 1:500-2000.
交叉反应 Human Mouse
蛋白分子量 56kDa
Gene ID 56852
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human RAD18
性状 液体
Public Immunogen Range Recombinant protein of human RAD18
Subcellular Locations Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center
Swiss Prot Q9NS91
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.