Anti-RAD18 Polyclonal Antibody
品牌：solarbio | 货号：K003956P
| 英文名称 | Anti-RAD18 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | RNF73 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 56kDa |
| Gene ID | 56852 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RAD18 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RAD18 |
| Subcellular Locations | Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center |
| Swiss Prot | Q9NS91 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |