Anti-RAD18 Polyclonal Antibody
品牌:solarbio | 货号:K003956P
英文名称 |
Anti-RAD18 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
RNF73 |
应用 |
WB |
稀释比例 |
WB 1:500-2000. |
交叉反应 |
Human Mouse |
蛋白分子量 |
56kDa |
Gene ID |
56852 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human RAD18 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human RAD18 |
Subcellular Locations |
Cytoplasm Nucleus centrosome cytoskeleton microtubule organizing center |
Swiss Prot |
Q9NS91 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. |