Anti-SAP18 Polyclonal Antibody
品牌:solarbio | 货号:K003792P
英文名称 |
Anti-SAP18 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
2HOR0202;SAP18P |
应用 |
WB IHC |
稀释比例 |
WB 1:200-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
18kDa |
Gene ID |
10284 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human SAP18 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human SAP18 |
Subcellular Locations |
Cytoplasm Nucleus Nucleus speckle |
Swiss Prot |
O00422 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. |