Anti-OGG1 Polyclonal Antibody
品牌：solarbio | 货号：K106890P
| 英文名称 | Anti-OGG1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HMMH;HOGG1;MUTM;OGH1;N-glycosylase/DNA lyase |
| 应用 | IHC |
| 稀释比例 | IHC 1:25-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 39kDa |
| Gene ID | 4968 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human OGG1 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human OGG1 |
| Subcellular Locations | Nucleus Cytoplasm |
| Swiss Prot | O15527 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. |