Anti-ARFGAP3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ARFGAP3 Polyclonal Antibody

品牌:solarbio | 货号:K005709P

英文名称 Anti-ARFGAP3 Polyclonal Antibody
宿主 Rabbit
别名 ARFGAP1
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse
蛋白分子量 57kDa
Gene ID 26286
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ARFGAP3
性状 液体
Public Immunogen Range Recombinant protein of human ARFGAP3
Subcellular Locations Cytoplasm Cytoplasmic side Golgi apparatus membrane Peripheral membrane protein
Swiss Prot Q9NP61
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.