Anti-ARFGAP3 Polyclonal Antibody
品牌:solarbio | 货号:K005709P
英文名称 |
Anti-ARFGAP3 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
ARFGAP1 |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-100. |
交叉反应 |
Human Mouse |
蛋白分子量 |
57kDa |
Gene ID |
26286 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human ARFGAP3 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human ARFGAP3 |
Subcellular Locations |
Cytoplasm Cytoplasmic side Golgi apparatus membrane Peripheral membrane protein |
Swiss Prot |
Q9NP61 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. |