Anti-VPS37A Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-VPS37A Polyclonal Antibody

品牌:solarbio | 货号:K005505P

英文名称 Anti-VPS37A Polyclonal Antibody
宿主 Rabbit
别名 HCRP1;PQBP2;SPG53
应用 WB IHC IF
稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 44kDa
Gene ID 137492
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human VPS37A
性状 液体
Public Immunogen Range Recombinant protein of human VPS37A
Subcellular Locations Late endosome membrane Nucleus Peripheral membrane protein
Swiss Prot Q8NEZ2
克隆类型 Polyclonal Antibody
背景资料 This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.