Anti-VPS37A Polyclonal Antibody
品牌:solarbio | 货号:K005505P
英文名称 |
Anti-VPS37A Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
HCRP1;PQBP2;SPG53 |
应用 |
WB IHC IF |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. IF 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
44kDa |
Gene ID |
137492 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human VPS37A |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human VPS37A |
Subcellular Locations |
Late endosome membrane Nucleus Peripheral membrane protein |
Swiss Prot |
Q8NEZ2 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene. |