Anti-PDHB Polyclonal Antibody
品牌：solarbio | 货号：K004882P
| 英文名称 | Anti-PDHB Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | PDHBD;PDHE1-B;PHE1B |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 39kDa |
| Gene ID | 5162 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PDHB |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PDHB |
| Subcellular Locations | Mitochondrion matrix |
| Swiss Prot | P11177 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. |