Anti-RASGRF1 Polyclonal Antibody
品牌：solarbio | 货号：K004898P
| 英文名称 | Anti-RASGRF1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CDC25;CDC25L;GNRP;GRF1;GRF55;H-GRF55;PP13187;ras-GRF1 |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 145kDa |
| Gene ID | 5923 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human RASGRF1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human RASGRF1 |
| Subcellular Locations | Cytosol Plasma Membrane |
| Swiss Prot | Q13972 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |