Anti-PEG10 Polyclonal Antibody
品牌:solarbio | 货号:K006818P
| 英文名称 | Anti-PEG10 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EDR;HB-1;Mar2;MEF3L;Mart2;RGAG3 |
| 应用 | WB |
| 稀释比例 | WB 1:200-1000. |
| 交叉反应 | Human |
| 蛋白分子量 | 80kDa |
| Gene ID | 23089 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PEG10 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human PEG10 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q86TG7 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. |