Anti-PEG10 Polyclonal Antibody
品牌:solarbio | 货号:K006818P
英文名称 |
Anti-PEG10 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
EDR;HB-1;Mar2;MEF3L;Mart2;RGAG3 |
应用 |
WB |
稀释比例 |
WB 1:200-1000. |
交叉反应 |
Human |
蛋白分子量 |
80kDa |
Gene ID |
23089 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human PEG10 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human PEG10 |
Subcellular Locations |
Nucleus |
Swiss Prot |
Q86TG7 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. |