Anti-PEG10 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-PEG10 Polyclonal Antibody

品牌:solarbio | 货号:K006818P

英文名称 Anti-PEG10 Polyclonal Antibody
宿主 Rabbit
别名 EDR;HB-1;Mar2;MEF3L;Mart2;RGAG3
应用 WB
稀释比例 WB 1:200-1000.
交叉反应 Human
蛋白分子量 80kDa
Gene ID 23089
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human PEG10
性状 液体
Public Immunogen Range Recombinant protein of human PEG10
Subcellular Locations Nucleus
Swiss Prot Q86TG7
克隆类型 Polyclonal Antibody
背景资料 This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.