Anti-CEACAM1 Polyclonal Antibody
品牌：solarbio | 货号：K006700P
| 英文名称 | Anti-CEACAM1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BGP;BGP1;BGPI |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:15-50. |
| 交叉反应 | Human |
| 蛋白分子量 | 58kDa |
| Gene ID | 634 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CEACAM1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CEACAM1 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P13688 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. |