Anti-ADD1 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-ADD1 Polyclonal Antibody

品牌:solarbio | 货号:K006638P

英文名称 Anti-ADD1 Polyclonal Antibody
宿主 Rabbit
别名 ADDA
应用 IHC
稀释比例 IHC 1:50-200.
交叉反应 Human Mouse Rat
蛋白分子量 81kDa
Gene ID 118
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human ADD1
性状 液体
Public Immunogen Range Recombinant protein of human ADD1
Subcellular Locations Cytoplasm
Swiss Prot P35611
克隆类型 Polyclonal Antibody
背景资料 Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.