Anti-XPC Polyclonal Antibody
品牌：solarbio | 货号：K007896P
| 英文名称 | Anti-XPC Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | XP3;RAD4;XPCC;p125 |
| 应用 | IHC |
| 稀释比例 | IHC 1:30-150. |
| 交叉反应 | Human |
| 蛋白分子量 | 102/16kDa |
| Gene ID | 7508 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human XPC |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human XPC |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q01831 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. |