Anti-BCL2L2 Polyclonal Antibody
品牌：solarbio | 货号：K007983P
| 英文名称 | Anti-BCL2L2 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | BCLW;BCL-W;PPP1R51;BCL2-L-2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:30-150. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 21kDa |
| Gene ID | 599 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human BCL2L2 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human BCL2L2 |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | Q92843 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. |