Anti-BGLAP Polyclonal Antibody
品牌:solarbio | 货号:K009392P
英文名称 |
Anti-BGLAP Polyclonal Antibody |
宿主 |
|
别名 |
BGP;OC;OCN;osteocalcin |
应用 |
WB |
稀释比例 |
WB 1:500 – 1:2000. |
交叉反应 |
Human,Mouse |
蛋白分子量 |
11kDa |
Gene ID |
632 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
A synthetic peptide of human BGLAP |
性状 |
液体 |
Public Immunogen Range |
A synthetic peptide of human BGLAP |
Subcellular Locations |
Secreted |
Swiss Prot |
P02818 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product. |