Anti-CD177 Polyclonal Antibody
品牌：solarbio | 货号：K004607P
| 英文名称 | Anti-CD177 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | HNA-2a;HNA2A;NB1;NB1 GP;PRV-1;PRV1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 46kDa |
| Gene ID | 57126 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD177 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD177 |
| Subcellular Locations | Cell membrane GPI-anchor Lipid-anchor |
| Swiss Prot | Q8N6Q3 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener’s granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. |