Anti-CD207 Polyclonal Antibody
品牌：solarbio | 货号：K004609P
| 英文名称 | Anti-CD207 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | CLEC4K |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 37kDa |
| Gene ID | 50489 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD207 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD207 |
| Subcellular Locations | Membrane Single-pass type II membrane protein |
| Swiss Prot | Q9UJ71 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. |