Anti-CDKN2D Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CDKN2D Polyclonal Antibody

品牌:solarbio | 货号:K004611P

英文名称 Anti-CDKN2D Polyclonal Antibody
宿主 Rabbit
别名 INK4D;p19;p19-INK4D
应用 WB IF
稀释比例 WB 1:500-2000. IF 1:50-100.
交叉反应 Human
蛋白分子量 18kDa
Gene ID 1032
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human CDKN2D
性状 液体
Public Immunogen Range Recombinant protein of human CDKN2D
Subcellular Locations Cytoplasm Nucleus
Swiss Prot P55273
克隆类型 Polyclonal Antibody
背景资料 The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.