Anti-CDKN2D Polyclonal Antibody
品牌：solarbio | 货号：K004611P
| 英文名称 | Anti-CDKN2D Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | INK4D;p19;p19-INK4D |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human |
| 蛋白分子量 | 18kDa |
| Gene ID | 1032 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CDKN2D |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CDKN2D |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | P55273 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. |