Anti-COL9A1 Polyclonal Antibody
品牌：solarbio | 货号：K004617P
| 英文名称 | Anti-COL9A1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DJ149L1.1.2;EDM6;MED;STL4 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 92kDa |
| Gene ID | 1297 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COL9A1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COL9A1 |
| Subcellular Locations | Secreted extracellular matrix extracellular space |
| Swiss Prot | P20849 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. |