Anti-KCNH1 Polyclonal Antibody
品牌：solarbio | 货号：K004674P
| 英文名称 | Anti-KCNH1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | EAG;EAG1;Kv10.1;TMBTS;ZLS1;h-eag;hEAG1 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 111kDa |
| Gene ID | 3756 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human KCNH1 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human KCNH1 |
| Subcellular Locations | Cell membrane Early endosome membrane Multi-pass membrane protein Nucleus inner membrane |
| Swiss Prot | O95259 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. |