Anti-MATK Polyclonal Antibody
品牌:solarbio | 货号:K004685P
英文名称 |
Anti-MATK Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CHK;CTK;HHYLTK;HYL;HYLTK;Lsk |
应用 |
WB IHC |
稀释比例 |
WB 1:500-2000. IHC 1:50-200. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
56kDa |
Gene ID |
4145 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human MATK |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human MATK |
Subcellular Locations |
Cytoplasm Membrane |
Swiss Prot |
P42679 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. |