Anti-IKZF3 Polyclonal Antibody
品牌：solarbio | 货号：K005140P
| 英文名称 | Anti-IKZF3 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | AIO;AIOLOS;ZNFN1A3 |
| 应用 | WB IF |
| 稀释比例 | WB 1:500-2000. IF 1:50-100. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 58kDa |
| Gene ID | 22806 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human IKZF3 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human IKZF3 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9UKT9 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. |