Anti-ZAK Polyclonal Antibody
品牌:solarbio | 货号:K005212P
| 英文名称 | Anti-ZAK Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | MAP3K20;ZAK;AZK;MLK7;MLT;MLTK;MLTKalpha;MLTKbeta;MRK;SFMMP;mlklak;pk; |
| 应用 | WB IHC IF |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:20-50. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 91kDa |
| Gene ID | 51776 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human ZAK |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human ZAK |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q9NYL2 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |