Anti-AKTIP Polyclonal Antibody
品牌：solarbio | 货号：K004380P
| 英文名称 | Anti-AKTIP Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | FT1;FTS |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 33kDa |
| Gene ID | 64400 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human AKTIP |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human AKTIP |
| Subcellular Locations | Cell membrane Cytoplasm Peripheral membrane protein |
| Swiss Prot | Q9H8T0 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB’s regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. |