Anti-COPS6 Polyclonal Antibody
品牌:solarbio | 货号:K004988P
英文名称 |
Anti-COPS6 Polyclonal Antibody |
宿主 |
Rabbit |
别名 |
CSN6;MOV34-34KD |
应用 |
WB IF |
稀释比例 |
WB 1:500-2000. IF 1:50-100. |
交叉反应 |
Human Mouse Rat |
蛋白分子量 |
36kDa |
Gene ID |
10980 |
保存 |
Store at -20°C. Avoid freeze / thaw cycles. |
储存液 |
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 |
Affinity purification |
亚型 |
IgG |
免疫原 |
Recombinant protein of human COPS6 |
性状 |
液体 |
Public Immunogen Range |
Recombinant protein of human COPS6 |
Subcellular Locations |
Cytoplasm Nucleus |
Swiss Prot |
Q7L5N1 |
克隆类型 |
Polyclonal Antibody |
背景资料 |
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. |