Anti-Smad4 Polyclonal Antibody
品牌：solarbio | 货号：K106653P
| 英文名称 | Anti-Smad4 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | DPC4;MADH4;Hsmad4;MAD homolog 4 |
| 应用 | IHC |
| 稀释比例 | IHC 1:50-200. |
| 交叉反应 | Mouse |
| 蛋白分子量 | 60kDa |
| Gene ID | 4089 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human Smad4 |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human Smad4 |
| Subcellular Locations | Cytoplasm Nucleus |
| Swiss Prot | Q13485 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. |