Anti-CXCR3 Polyclonal Antibody-一抗-抗体-蛋白与免疫

Anti-CXCR3 Polyclonal Antibody

品牌:solarbio | 货号:K003535P

英文名称 Anti-CXCR3 Polyclonal Antibody
宿主 Rabbit
别名 CD182;CD183;CKR-L2;CMKAR3;GPR9;IP10-R;Mig-R;MigR
应用 WB IHC
稀释比例 WB 1:500-2000. IHC 1:50-100.
交叉反应 Human Mouse
蛋白分子量 41kDa
Gene ID 2833
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 A synthetic peptide of human CXCR3
性状 液体
Public Immunogen Range A synthetic peptide of human CXCR3
Subcellular Locations Cell membrane Multi-pass membrane protein
Swiss Prot P49682
克隆类型 Polyclonal Antibody
背景资料 This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).