Anti-DCT Polyclonal Antibody
品牌:solarbio | 货号:K006848P
| 英文名称 | Anti-DCT Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 别名 | TRP-2;TYRP2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse |
| 蛋白分子量 | 59kDa |
| Gene ID | 1638 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human DCT |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human DCT |
| Subcellular Locations | Cytoplasm |
| Swiss Prot | P40126 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as?DCT, is a human?gene. The human TYRP2 protein has 83% identity and 90% similarity to the mouse sequence and has all the structural characteristics of the tyrosinase protein family, including a signal peptide, 15 conserved cysteine residues, 2 copper-binding domains, and a C-terminal membrane-spanning region. Northern blot analysis showed that TYRP2 is expressed at high levels in human melanoma cells. Its expression is regulated by the microphthalmia-associated transcription factor (MITF). |